Paediatric pulmonary arterial hypertension (PAH) shares common features of adult disease,
but is associated with several additional disorders and challenges that require unique …

Pulmonary hypertension (PH) is a rare disease in newborns, infants, and children that is
associated with significant morbidity and mortality. In the majority of pediatric patients, PH is …

Abstract With a prevalence of 2.6–4.5%, infantile haemangiomas (IH) represent the most
common tumour of infancy. While the majority of IH does not require therapy and regresses …

Thus, the task of writing Guidelines or Expert Consensus documents covers not only the
integration of the most recent research, but also the creation of educational tools and …

Background: Cardiac injury and myocarditis have been described in adults with coronavirus
disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Background Valved conduits from the right ventricle to the pulmonary artery are frequently
used in paediatric cardiac surgery. However, stenosis and insufficiency of the conduit …

Background Epidemiological studies suggest that obesity-induced atherosclerosis may start
in childhood, but this process has never been demonstrated. We looked for arterial changes …

Holt-Oram syndrome is a developmental disorder affecting the heart and upper limb, the
gene for which was mapped to chromosome 12 two years ago. We have now identified a …

The human peripheral B-cell compartment displays a large population of immunoglobulin M–
positive, immunoglobulin D–positive CD27+ (IgM+ IgD+ CD27+)“memory” B cells carrying a …

Background—Transposition of the great arteries (TGA) is a life-threatening malformation in
neonates, but it is amenable to complete repair. Prenatal detection, diagnosis, and early …