User profiles for "author:D R Love"

Donald R. Love

Division Chief, Pathology Genetics, Sidra Medicine
Verified email at sidra.org
Cited by 15248

Chemical discovery and global gene expression analysis in zebrafish

FB Pichler, S Laurenson, LC Williams, A Dodd… - Nature …, 2003 - nature.com
The zebrafish (Danio rerio) provides an excellent model for studying vertebrate development
and human disease because of its ex utero, optically transparent embryogenesis and …

Zebrafish: bridging the gap between development and disease

A Dodd, PM Curtis, LC Williams… - Human molecular …, 2000 - academic.oup.com
The zebrafish has been the model of choice amongst developmental biologists for many
years. This small freshwater species offers many advantages to the study of organ and …

Technology for high-throughput screens: the present and future using zebrafish

DR Love, FB Pichler, A Dodd, BR Copp… - Current opinion in …, 2004 - Elsevier
The zebrafish is a popular vertebrate model organism with similar organ systems and gene
sequences to humans. Zebrafish embryos are optically transparent enabling organ …

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

LM Mulligan, JBJ Kwok, CS Healey, MJ Elsdon, C Eng… - Nature, 1993 - nature.com
MULTIPLE endocrine neoplasia type 2A (MEN 2A) is a dominantly inherited cancer
syndrome that affects tissues derived from neural ectoderm. It is characterized by medullary …

[HTML][HTML] A prospective study of sudden cardiac death among children and young adults

RD Bagnall, RG Weintraub, J Ingles… - … England Journal of …, 2016 - Mass Medical Soc
Background Sudden cardiac death among children and young adults is a devastating event.
We performed a prospective, population-based, clinical and genetic study of sudden cardiac …

Validation of Zebrafish (Danio rerio) Reference Genes for Quantitative Real-time RT-PCR Normalization

R Tang, A Dodd, D Lai, WC McNabb… - Acta biochimica et …, 2007 - academic.oup.com
The normalization of quantitative real time RT-PCR (qRT-PCR) is important to obtain
accurate gene expression data. The most common method for qRT-PCR normalization is to …

An autosomal transcript in skeletal muscle with homology to dystrophin

DR Love, DF Hill, G Dickson, NK Spurr, BC Byth… - Nature, 1989 - nature.com
THE Duchenne muscular dystrophy (DMD) gene has been localized to chromosome Xp211–
6 and codes for a 14-kilobase (kb) transcript7 and a protein called dystrophin8, of relative …

Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs

G Acsadi, G Dickson, DR Love, A Jani, FS Walsh… - Nature, 1991 - nature.com
Abstract DUCHENNE'S muscular dystrophy (DMD), which affects one in 3,500 males,
causes progressive myopathy of skeletal and cardiac muscles and premature death1. One …

Very mild muscular dystrophy associated with the deletion of 46% of dystrophin

SB England, LVB Nicholson, MA Johnson, SM Forrest… - Nature, 1990 - nature.com
DUCHENNE muscular dystrophy (DMD) 1 and Becker muscular dystrophy (BMD), a much
milder form of the disease where the age of onset can sometimes be as late as the third or …

Primary structure of dystrophin-related protein

JM Tinsley, DJ Blake, A Roche, U Fairbrother, J Riss… - Nature, 1992 - nature.com
Abstract DYSTROPHIN-RELATED protein (DRP or'utrophin'1) is localized in normal adult
muscle primarily at the neuromuscular junction2–4. In the absence of dystrophin in …