User profiles for "author:D R Love"
Donald R. LoveDivision Chief, Pathology Genetics, Sidra Medicine Verified email at sidra.org Cited by 15248 |
Chemical discovery and global gene expression analysis in zebrafish
FB Pichler, S Laurenson, LC Williams, A Dodd… - Nature …, 2003 - nature.com
The zebrafish (Danio rerio) provides an excellent model for studying vertebrate development
and human disease because of its ex utero, optically transparent embryogenesis and …
and human disease because of its ex utero, optically transparent embryogenesis and …
Zebrafish: bridging the gap between development and disease
A Dodd, PM Curtis, LC Williams… - Human molecular …, 2000 - academic.oup.com
The zebrafish has been the model of choice amongst developmental biologists for many
years. This small freshwater species offers many advantages to the study of organ and …
years. This small freshwater species offers many advantages to the study of organ and …
Technology for high-throughput screens: the present and future using zebrafish
The zebrafish is a popular vertebrate model organism with similar organ systems and gene
sequences to humans. Zebrafish embryos are optically transparent enabling organ …
sequences to humans. Zebrafish embryos are optically transparent enabling organ …
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
LM Mulligan, JBJ Kwok, CS Healey, MJ Elsdon, C Eng… - Nature, 1993 - nature.com
MULTIPLE endocrine neoplasia type 2A (MEN 2A) is a dominantly inherited cancer
syndrome that affects tissues derived from neural ectoderm. It is characterized by medullary …
syndrome that affects tissues derived from neural ectoderm. It is characterized by medullary …
[HTML][HTML] A prospective study of sudden cardiac death among children and young adults
RD Bagnall, RG Weintraub, J Ingles… - … England Journal of …, 2016 - Mass Medical Soc
Background Sudden cardiac death among children and young adults is a devastating event.
We performed a prospective, population-based, clinical and genetic study of sudden cardiac …
We performed a prospective, population-based, clinical and genetic study of sudden cardiac …
Validation of Zebrafish (Danio rerio) Reference Genes for Quantitative Real-time RT-PCR Normalization
The normalization of quantitative real time RT-PCR (qRT-PCR) is important to obtain
accurate gene expression data. The most common method for qRT-PCR normalization is to …
accurate gene expression data. The most common method for qRT-PCR normalization is to …
An autosomal transcript in skeletal muscle with homology to dystrophin
DR Love, DF Hill, G Dickson, NK Spurr, BC Byth… - Nature, 1989 - nature.com
THE Duchenne muscular dystrophy (DMD) gene has been localized to chromosome Xp211–
6 and codes for a 14-kilobase (kb) transcript7 and a protein called dystrophin8, of relative …
6 and codes for a 14-kilobase (kb) transcript7 and a protein called dystrophin8, of relative …
Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs
Abstract DUCHENNE'S muscular dystrophy (DMD), which affects one in 3,500 males,
causes progressive myopathy of skeletal and cardiac muscles and premature death1. One …
causes progressive myopathy of skeletal and cardiac muscles and premature death1. One …
Very mild muscular dystrophy associated with the deletion of 46% of dystrophin
SB England, LVB Nicholson, MA Johnson, SM Forrest… - Nature, 1990 - nature.com
DUCHENNE muscular dystrophy (DMD) 1 and Becker muscular dystrophy (BMD), a much
milder form of the disease where the age of onset can sometimes be as late as the third or …
milder form of the disease where the age of onset can sometimes be as late as the third or …
Primary structure of dystrophin-related protein
JM Tinsley, DJ Blake, A Roche, U Fairbrother, J Riss… - Nature, 1992 - nature.com
Abstract DYSTROPHIN-RELATED protein (DRP or'utrophin'1) is localized in normal adult
muscle primarily at the neuromuscular junction2–4. In the absence of dystrophin in …
muscle primarily at the neuromuscular junction2–4. In the absence of dystrophin in …