Many active organic compounds and organic effect materials are poorly soluble in water, or
even insoluble. Aqueous forms of application thus require special formulation techniques to …

This analysis describes the epidemiology and outcomes of candidemia in patients enrolled
in the Prospective Antifungal Therapy Alliance (PATH Alliance®) registry from 2004 to 2008 …

The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …

Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the
diploid genome contains a predicted 22,570 proteins encoded by genes, of which 12,570 …

Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …

Mammalian genomes are organized into megabase-scale topologically associated domains
(TADs). We demonstrate that disruption of TADs can rewire long-range regulatory …

Background The genetic cause of intellectual disability in most patients is unclear because
of the absence of morphological clues, information about the position of such genes, and …

Background. With use of data from the Prospective Antifungal Therapy (PATH) Alliance
registry, we performed this multicenter, prospective, observational study to assess the …

We present a novel clustering method using the approach of support vector machines. Data
points are mapped by means of a Gaussian kernel to a high dimensional feature space …

Background. Candidemia remains a major cause of morbidity and mortality in the health
care setting, and the epidemiology of Candida infection is changing. Methods. Clinical data …