A genetic study of von Recklinghausen neurofibromatosis in south east Wales. II. Guidelines for genetic counselling.
SM Huson, DA Compston, PS Harper - Journal of medical genetics, 1989 - jmg.bmj.com
The age of appearance and diagnostic value of the major defining features of von
Recklinghausen neurofibromatosis (NF-1) have been studied in 168 cases from 73 families …
Recklinghausen neurofibromatosis (NF-1) have been studied in 168 cases from 73 families …
The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy
Abstract From 1991–2002, we treated 58 patients with multiple sclerosis (MS) using the
humanised monoclonal antibody, Campath–1H, which causes prolonged T lymphocyte …
humanised monoclonal antibody, Campath–1H, which causes prolonged T lymphocyte …
A genetic study of von Recklinghausen neurofibromatosis in south east Wales. I. Prevalence, fitness, mutation rate, and effect of parental transmission on severity.
SM Huson, DA Compston, P Clark… - Journal of medical …, 1989 - jmg.bmj.com
A population based study of von Recklinghausen neurofibromatosis in south east Wales
(population 668,100) identified 69 families with 135 affected members (prevalence 1/4950 of …
(population 668,100) identified 69 families with 135 affected members (prevalence 1/4950 of …
A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects.
NM Milligan, R Newcombe… - Journal of Neurology …, 1987 - jnnp.bmj.com
A randomised double-blind, placebo-controlled trial of high-dose, pulsed intravenous
methylprednisolone was carried out in 50 individuals with multiple sclerosis; 22 patients …
methylprednisolone was carried out in 50 individuals with multiple sclerosis; 22 patients …
EDMUS, a European database for multiple sclerosis.
C Confavreux, DA Compston, OR Hommes… - Journal of Neurology …, 1992 - jnnp.bmj.com
EDMUS is a minimal descriptive record developed for research purposes to document
clinical and laboratory data in patients with multiple sclerosis (MS). It has been designed by …
clinical and laboratory data in patients with multiple sclerosis (MS). It has been designed by …
Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity
JL Jones, JM Anderson, CL Phuah, EJ Fox, K Selmaj… - Brain, 2010 - academic.oup.com
Abstract Treatment of early relapsing–remitting multiple sclerosis with the lymphocyte-
depleting humanized monoclonal antibody alemtuzumab (Campath [registered trade mark]) …
depleting humanized monoclonal antibody alemtuzumab (Campath [registered trade mark]) …
A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow-up.
DA Francis, DA Compston, JR Batchelor… - Journal of Neurology …, 1987 - jnnp.bmj.com
One hundred and one of 146 patients presenting with isolated idiopathic optic neuritis,
previously reviewed in 1978, were reassessed clinically, and retyped for HLA antigens and …
previously reviewed in 1978, were reassessed clinically, and retyped for HLA antigens and …
Symptomatic Epstein-Barr virus infection and multiple sclerosis.
CN Martyn, M Cruddas, DA Compston - Journal of Neurology …, 1993 - jnnp.bmj.com
In a case-control study of 214 patients with multiple sclerosis, recall of infectious
mononucleosis in subjects seropositive for Epstein-Barr viral capsid antigen was associated …
mononucleosis in subjects seropositive for Epstein-Barr viral capsid antigen was associated …
Failure to achieve remyelination of demyelinated rat axons following transplantation of glial cells obtained from the adult human brain.
MP Targett, J Sussman, N Scolding… - Neuropathology and …, 1996 - europepmc.org
The ability of transplanted glial cells to myelinate axons in experimental animals offers the
prospect that it may be possible to achieve remyelination in human demyelinating disease …
prospect that it may be possible to achieve remyelination in human demyelinating disease …
Microglia-derived IGF-2 prevents TNFα induced death of mature oligodendrocytes in vitro
RS Nicholas, S Stevens, MG Wing… - Journal of …, 2002 - Elsevier
Insulin-like growth factor-2 (IGF-2) present in media conditioned by non-activated and
interferon gamma (IFNγ)-treated microglia reduces galactocerebroside+ (GalC) …
interferon gamma (IFNγ)-treated microglia reduces galactocerebroside+ (GalC) …