User profiles for "author:Catherine Goudie"

Catherine Goudie

Assistant Professor, McGill University
Verified email at mcgill.ca
Cited by 572

Small-cell carcinoma of the ovary of hypercalcemic type (malignant rhabdoid tumor of the ovary): a review with recent developments on pathogenesis

L Witkowski, C Goudie, WD Foulkes… - Surgical pathology …, 2016 - Elsevier
Small-cell carcinoma of the ovary of hypercalcemic type (SCCOHT) is a highly malignant
and aggressive tumor and is the most common undifferentiated ovarian malignancy to occur …

[HTML][HTML] The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations

A Villani, S Davidson, N Kanwar, WW Lo, Y Li… - Nature Cancer, 2023 - nature.com
We conducted integrative somatic–germline analyses by deeply sequencing 864 cancer-
associated genes, complete genomes and transcriptomes for 300 mostly previously treated …

The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type

L Witkowski, C Goudie, P Ramos, T Boshari… - Gynecologic …, 2016 - Elsevier
Objective Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is an aggressive
tumor, with long term survival at~ 30% in early stage disease. SCCOHT is caused by …

[HTML][HTML] Survival benefit for individuals with constitutional mismatch repair deficiency undergoing surveillance

C Durno, AB Ercan, V Bianchi, M Edwards… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
PURPOSE Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer
predisposition syndrome characterized by early-onset synchronous and metachronous …

Performance of the McGill interactive pediatric oncogenetic guidelines for identifying cancer predisposition syndromes

C Goudie, L Witkowski, N Cullinan, L Reichman… - JAMA …, 2021 - jamanetwork.com
Importance Prompt recognition of a child with a cancer predisposition syndrome (CPS) has
implications for cancer management, surveillance, genetic counseling, and cascade testing …

A systematic review of the prevalence of pathogenic or likely pathogenic germline variants in individuals with FOXO1 fusion‐positive rhabdomyosarcoma

C Freycon, PJ Lupo, L Witkowski, C Budd… - Pediatric Blood & …, 2023 - Wiley Online Library
Several cancer predisposition syndromes (CPS) are reported to predispose to
rhabdomyosarcoma, most frequently in children with embryonal rhabdomyosarcoma. There …

[HTML][HTML] Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor

S Fahiminiya, L Witkowski, J Nadaf, J Carrot-Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is the most common
undifferentiated ovarian malignancy diagnosed in women under age 40. We and others …

Paediatric ovarian tumours and their associated cancer susceptibility syndromes

C Goudie, L Witkowski, S Vairy… - Journal of Medical …, 2018 - jmg.bmj.com
Non-epithelial ovarian tumours are rare neoplasms that occasionally arise in childhood and
adolescence. They can be associated with various cancer susceptibility syndromes. The …

The McGill Interactive Pediatric OncoGenetic Guidelines: an approach to identifying pediatric oncology patients most likely to benefit from a genetic evaluation

C Goudie, H Coltin, L Witkowski… - Pediatric blood & …, 2017 - Wiley Online Library
Identifying cancer predisposition syndromes in children with tumors is crucial, yet few clinical
guidelines exist to identify children at high risk of having germline mutations. The McGill …

[HTML][HTML] Sequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma

L De Kock, B Rivera, T Revil, P Thorner… - British Journal of …, 2017 - nature.com
Background: Sarcomas are rare and heterogeneous cancers. We assessed the contribution
of DICER1 mutations to sarcoma development. Methods: The coding region of DICER1 was …