Objective This work was undertaken in order to identify Parkinson's disease (PD) risk
variants in a Latino cohort, to describe the overlap in the genetic architecture of PD in …

Background Wiedemann-Rautenstrauch syndrome (WRS) is a form of segmental progeria
presenting neonatally, characterised by growth retardation, sparse scalp hair, generalised …

Background Parkinson's disease is the second most common neurodegenerative disorder
and affects people from all ethnic backgrounds, yet little is known about the genetics of …

Recently, mutations in the RNA polymerase III subunit A (POLR3A) have been described as
the cause of the neonatal progeria or Wiedemann-Rautenstrauch syndrome (WRS) …

Objective: We evaluated the association of several single-nucleotide polymorphisms in
different genes including APOE, TOMM40, CR1, PVRL2, SORL1, PICALM, and …

The Drosophila cold acclimation gene (Dca) is involved in the adaptive response to low
temperatures. This gene is upregulated at the transcriptional level when D. melanogaster …

Objective: The objective of this study was to evaluate the BIN1 3′ intergenic region DNA
methylation patterns in a Colombian sample of LOAD patients. Methods: A case-control …

Background: The Apolipoprotein E (APOE) gene is the main risk factor for late-onset
Alzheimer disease (LOAD). Genetic variants and haplotypes in regions near the APOE locus …

Objective: We evaluated the association of several single-nucleotide polymorphisms in the
triggering receptor expressed on myeloid cells 2 (TREM2) gene in a Colombian sample of …

In adulthood, the ability to digest lactose, the main sugar present in milk of mammals, is a
phenotype (lactase persistence) observed in historically herder populations, mainly …