Background Inherited mutations in DNA mismatch repair genes predispose to different
cancer syndromes depending on whether they are mono-allelic or bi-allelic. This supports a …

The pathogenesis of lung hypoplasia in congenital diaphragmatic hernia (CDH), a common
birth defect, is poorly understood. The diaphragmatic defect can be repaired surgically, but …

Methods: A comprehensive chart review of all children with diagnosed as having IBD
between January 2006 and August 2014 was performed. Patients with PE at diagnosis were …

Background Human tissue samples are an invaluable and little available source of
information for translational studies of congenital lung diseases such as Congenital …

Myxoinflammatory fibroblastic sarcoma (MIFS), originally described as a low-grade
malignant soft-tissue tumor in adults, has recently been reported in children and in non-acral …

Background Workload measurement is important to help determine optimal staffing and
workload distribution for pathology laboratories. The Level 4 Equivalent (L4E) System is the …

In Response: There is a note of irony in the correspondence by de Chadarevian et al1 who
reported and illustrated the presence of trisomy 8 in a case of fetal lung interstitial tumor …

Inflammatory myofibroblastic tumors (IMTs) are rare tumors with an intermediate spectrum of
biological behavior. IMTs are uncommon secondary malignancies after hematopoietic stem …

Objectives: Although it has been recommended to perform sigmoidoscopy to screen for
cytomegalovirus (CMV) reactivation in acute severe colitis, the frequency of CMV …

Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive malignancy typically
occurring intra-abdominally in young adolescent males. Rare extra-abdominal primaries …