Guidelines for the management of inflammatory bowel disease in adults
The management of inflammatory bowel disease represents a key component of clinical
practice for members of the British Society of Gastroenterology (BSG). There has been …
practice for members of the British Society of Gastroenterology (BSG). There has been …
New IBD genetics: common pathways with other diseases
Complex disease genetics has been revolutionised in recent years by the advent of genome-
wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's …
wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's …
[HTML][HTML] Peer reviewed: effect of aerobic exercise on cognition, academic achievement, and psychosocial function in children: a systematic review of randomized …
C Lees, J Hopkins - Preventing chronic disease, 2013 - ncbi.nlm.nih.gov
Methods A systematic review of English articles was performed in April 2013 using
MEDLINE, Cochrane, PsycINFO, SPORTDiscus, and EMBASE. Additional studies were …
MEDLINE, Cochrane, PsycINFO, SPORTDiscus, and EMBASE. Additional studies were …
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis …
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust
Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs …
Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs …
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Genetic association studies have identified 215 risk loci for inflammatory bowel disease,,,,,,,,
thereby uncovering fundamental aspects of its molecular biology. We performed a genome …
thereby uncovering fundamental aspects of its molecular biology. We performed a genome …
The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality
PA Taylor, CJ Lees, BR Blazar - Blood, The Journal of the …, 2002 - ashpublications.org
Immune regulatory CD4+ CD25+ cells play a vital role in the induction and maintenance of
self-tolerance and the prevention of autoimmunity. Recently, CD4+ CD25+ cells have been …
self-tolerance and the prevention of autoimmunity. Recently, CD4+ CD25+ cells have been …
Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease
6.1. Background The incidence of tuberculosis (TB) is a concern at the start of the third
millennium, particularly with the increase of multiresistant (MDR-TB) and extended resistant …
millennium, particularly with the increase of multiresistant (MDR-TB) and extended resistant …