User profiles for "author:Benjamin Nota"

Benjamin Nota

Verified email at sanquin.nl
Cited by 2812

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

LK Mackay, M Minnich, NAM Kragten, Y Liao, B Nota… - Science, 2016 - science.org
Tissue-resident memory T (Trm) cells permanently localize to portals of pathogen entry,
where they provide immediate protection against reinfection. To enforce tissue retention …

[HTML][HTML] Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

P Hombrink, C Helbig, RA Backer, B Piet, AE Oja… - Nature …, 2016 - nature.com
Tissue-resident memory T cells (TRM cells) in the airways mediate protection against
respiratory infection. We characterized TRM cells expressing integrin αE (CD103) that reside …

Hobit identifies tissue-resident memory T cell precursors that are regulated by Eomes

L Parga-Vidal, FM Behr, NAM Kragten, B Nota… - Science …, 2021 - science.org
Tissue-resident memory CD8+ T cells (TRM) constitute a noncirculating memory T cell
subset that provides early protection against reinfection. However, how TRM arise from …

[PDF][PDF] Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2-and L-2-hydroxyglutaric aciduria

B Nota, EA Struys, A Pop, EE Jansen… - The American Journal of …, 2013 - cell.com
The Krebs cycle is of fundamental importance for the generation of the energetic and
molecular needs of both prokaryotic and eukaryotic cells. Both enantiomers of metabolite 2 …

[HTML][HTML] Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8+ T Cells in the Lungs

FM Behr, NAM Kragten, TH Wesselink, B Nota… - Frontiers in …, 2019 - frontiersin.org
Tissue-resident memory CD8+ T (TRM) cells that develop in the epithelia at portals of
pathogen entry are important for improved protection against re-infection. CD8+ TRM cells …

Adaptive differences in gene expression associated with heavy metal tolerance in the soil arthropod Orchesella cincta

D Roelofs, TKS Janssens… - Molecular …, 2009 - Wiley Online Library
Field‐selected tolerance to heavy metals has been reported for Orchesella cincta
(Arthropoda: Collembola) populations occurring at metal‐contaminated mining sites. This …

An overview of combined D‐2‐and L‐2‐hydroxyglutaric aciduria: Functional analysis of CIC variants

A Pop, M Williams, EA Struys, M Monné… - Journal of Inherited …, 2018 - Wiley Online Library
Abstract Combined D‐2‐and L‐2‐hydroxyglutaric aciduria (D/L‐2‐HGA) is a devastating
neurometabolic disorder, usually lethal in the first years of life. Autosomal recessive …

[HTML][HTML] Reference genes for QRT-PCR tested under various stress conditions in Folsomia candida and Orchesella cincta (Insecta, Collembola)

ME de Boer, TE de Boer, J Mariën… - BMC Molecular …, 2009 - Springer
Background Genomic studies measuring transcriptional responses to changing
environments and stress currently make their way into the field of evolutionary ecology and …

[HTML][HTML] Transcriptomics reveals extensive inducible biotransformation in the soil-dwelling invertebrate Folsomia candida exposed to phenanthrene

B Nota, M Bosse, B Ylstra, NM van Straalen, D Roelofs - Bmc Genomics, 2009 - Springer
Background Polycyclic aromatic hydrocarbons are common pollutants in soil, have negative
effects on soil ecosystems, and are potentially carcinogenic. The Springtail (Collembola) …

Gene expression analysis of collembola in cadmium containing soil

B Nota, MJTN Timmermans, O Franken… - Environmental …, 2008 - ACS Publications
Increasing concern about pollution of our environment calls for advanced and rapid methods
to estimate ecological toxicity. The use of gene expression microarrays in environmental …