User profiles for "author:B Dutrillaux"
 | Bernard DutrillauxResearch director emeritus MNHN Verified email at mnhn.fr Cited by 27951 |
Common fragile sites: mechanisms of instability revisited
M Debatisse, B Le Tallec, A Letessier, B Dutrillaux… - Trends in Genetics, 2012 - cell.com
Common fragile sites (CFSs) are large chromosomal regions prone to breakage upon
replication stress that are considered a driving force of oncogenesis. CFSs were long …
replication stress that are considered a driving force of oncogenesis. CFSs were long …
Chromosomal evolution in Primates: Tentative phylogeny from Microcebus murinus (Prosimian) to man
B Dutrillaux - Human genetics, 1979 - Springer
The karyotypes of more than 60 species of Primates are studied and compared, with the use
of almost all existing banding techniques. There is a very close analogy of chromosome …
of almost all existing banding techniques. There is a very close analogy of chromosome …
Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
…, C Trucco, M Ricoul, B Dutrillaux… - Proceedings of the …, 1997 - National Acad Sciences
Poly (ADP-ribose) polymerase [PARP; NAD+ ADP-ribosyltransferase; NAD+: poly
(adenosine-diphosphate-d-ribosyl)-acceptor ADP-d-ribosyltransferase, EC 2.4. 2.30] is a …
(adenosine-diphosphate-d-ribosyl)-acceptor ADP-d-ribosyltransferase, EC 2.4. 2.30] is a …
Characterization of chromosomal anomalies in human breast cancer: a comparison of 30 paradiploid cases with few chromosome changes
B Dutrillaux, M Gerbault-Seureau, B Zafrani - Cancer genetics and …, 1990 - Elsevier
A comparison of chromosomal anomalies detected in 30 cases of breast cancer in females
with near-diploid karyotypes is reported. The tumors, of which 20 were previously …
with near-diploid karyotypes is reported. The tumors, of which 20 were previously …
Preferential binding of a G-quadruplex ligand to human chromosome ends
The G-overhangs of telomeres are thought to adopt particular conformations, such as T-
loops or G-quadruplexes. It has been suggested that G-quadruplex structures could be …
loops or G-quadruplexes. It has been suggested that G-quadruplex structures could be …
[PDF][PDF] Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes
B Le Tallec, GA Millot, ME Blin, O Brison, B Dutrillaux… - Cell reports, 2013 - cell.com
Cancer genomes exhibit numerous deletions, some of which inactivate tumor suppressor
genes and/or correspond to unstable genomic regions, notably common fragile sites (CFSs) …
genes and/or correspond to unstable genomic regions, notably common fragile sites (CFSs) …
Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours
…, J Lebeau, MF Poupon, S Oudard, B Dutrillaux… - Oncogene, 1998 - nature.com
The human OGG1 gene encodes a DNA glycosylase activity catalysing the excision of the
mutagenic lesion 7, 8-dihydro-8-oxoguanine from oxidatively damaged DNA. The OGG1 …
mutagenic lesion 7, 8-dihydro-8-oxoguanine from oxidatively damaged DNA. The OGG1 …
Establishment of human colon cancer cell lines from fresh tumors versus xenografts: comparison of success rate and cell line features
…, JL Janneau, N Auger, P Validire, B Dutrillaux… - Cancer research, 2007 - AACR
Obtaining representative human colon cancer cell lines from fresh tumors is technically
difficult. Using 32 tumor fragments from patients with colon cancer, the present study shows …
difficult. Using 32 tumor fragments from patients with colon cancer, the present study shows …
Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas
…, P Leuraud, MF Poupon, B Dutrillaux… - Proceedings of the …, 2004 - National Acad Sciences
Amplification of the epidermal growth factor receptor gene on double minutes is recurrently
observed in cells of advanced gliomas, but the structure of these extrachromosomal circular …
observed in cells of advanced gliomas, but the structure of these extrachromosomal circular …
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines
We describe the isolation and characterization of NSD3, the third member of a gene family
including Nsd1 and NSD2. Murine Nsd1 was isolated in a search for proteins that interact …
including Nsd1 and NSD2. Murine Nsd1 was isolated in a search for proteins that interact …