Biology, clinical characteristics, and management of adrenocortical tumors in children
C Rodriguez‐Galindo, BC Figueiredo… - Pediatric blood & …, 2005 - Wiley Online Library
Childhood adrenocortical tumors (ACT) are very aggressive endocrine neoplasms whose
incidence is quite low. Little is known about their pathogenesis, clinical presentation, and …
incidence is quite low. Little is known about their pathogenesis, clinical presentation, and …
[HTML][HTML] Adrenocortical tumors in children
RC Ribeiro, EL Michalkiewicz… - Brazilian Journal of …, 2000 - SciELO Brasil
Childhood adrenocortical tumors (ACT) are rare. In the USA, only about 25 new cases occur
each year. In Southern Brazil, however, approximately 10 times that many cases are …
each year. In Southern Brazil, however, approximately 10 times that many cases are …
[HTML][HTML] Pediatric adrenocortical tumors: what they can tell us on adrenal development and comparison with adult adrenal tumors
E Lalli, BC Figueiredo - Frontiers in Endocrinology, 2015 - frontiersin.org
Adrenocortical tumors (ACT) in children are very rare and are most frequently diagnosed in
the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline …
the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline …
Regulation of insulin-like growth factor–mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors
M Doghman, AEL Wakil, B Cardinaud, E Thomas… - Cancer research, 2010 - AACR
MicroRNAs (miRNAs) act at the posttranscriptional level to control gene expression in
virtually every biological process, including oncogenesis. Here, we report the identification …
virtually every biological process, including oncogenesis. Here, we report the identification …
[HTML][HTML] Impact of neonatal screening and surveillance for the TP53 R337H mutation on early detection of childhood adrenocortical tumors
G Custódio, GA Parise, N Kiesel Filho… - Journal of Clinical …, 2013 - ncbi.nlm.nih.gov
Impact of Neonatal Screening and Surveillance for the TP53 R337H Mutation on Early
Detection of Childhood Adrenocortical Tumors - PMC Back to Top Skip to main content NIH …
Detection of Childhood Adrenocortical Tumors - PMC Back to Top Skip to main content NIH …
Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer
M Doghman, T Karpova, GA Rodrigues… - Molecular …, 2007 - academic.oup.com
Abstract Steroidogenic factor-1 (SF-1/Ad4BP; NR5A1), a nuclear receptor transcription
factor, has a pivotal role in adrenal and gonadal development in humans and mice. A …
factor, has a pivotal role in adrenal and gonadal development in humans and mice. A …
[HTML][HTML] Genomic landscape of paediatric adrenocortical tumours
Paediatric adrenocortical carcinoma is a rare malignancy with poor prognosis. Here we
analyse 37 adrenocortical tumours (ACTs) by whole-genome, whole-exome and/or …
analyse 37 adrenocortical tumours (ACTs) by whole-genome, whole-exome and/or …
Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation
BC Figueiredo, R Sandrini, GP Zambetti… - Journal of medical …, 2006 - jmg.bmj.com
Background: An inherited germline P53 mutation has been identified in cases of childhood
adrenocortical carcinoma (ACT), a neoplasm with a high incidence in southern Brazil. The …
adrenocortical carcinoma (ACT), a neoplasm with a high incidence in southern Brazil. The …
Amplification of the steroidogenic factor 1 gene in childhood adrenocortical tumors
BC Figueiredo, LR Cavalli… - The Journal of …, 2005 - academic.oup.com
Southern Brazil has one of the highest incidences of childhood adrenocortical tumors
(ACTs), occurring 10–15 times more frequently than worldwide estimates. The reasons for …
(ACTs), occurring 10–15 times more frequently than worldwide estimates. The reasons for …
Comparative genomic hybridization analysis of adrenocortical tumors of childhood
BC Figueiredo, CA Stratakis, R Sandrini… - The Journal of …, 1999 - academic.oup.com
Although several genes have been investigated in adrenal tumorigenesis, the genetic
background of adrenocortical tumors (ACT) remains poorly characterized. In southern Brazil …
background of adrenocortical tumors (ACT) remains poorly characterized. In southern Brazil …