User profiles for "author:Artemio Payá"

Artemio Payá Romá

Hospital General Universitario de Alicante
Verified email at gva.es
Cited by 4564

Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal …

V Pińol, A Castells, M Andreu, S Castellví-Bel… - Jama, 2005 - jamanetwork.com
ContextThe selection of individuals for hereditary nonpolyposis colorectal cancer (HNPCC)
genetic testing is challenging. Recently, the National Cancer Institute outlined a new set of …

[HTML][HTML] Serrated polyposis syndrome: molecular, pathological and clinical aspects

C Guarinos, C Sánchez-Fortún… - World journal of …, 2012 - ncbi.nlm.nih.gov
Hyperplastic polyps have traditionally been considered not to have malignant potential. New
pathological classification of serrated polyps and recent discoveries about the serrated …

Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer

R Jover, P Zapater, A Castells, X Llor, M Andreu… - Gut, 2006 - gut.bmj.com
Aim: Some retrospective studies have shown a lack of benefit of 5-fluorouracil (5-FU)
adjuvant chemotherapy in patients with mismatch repair (MMR) deficient colorectal cancer …

Risk of cancer in cases of suspected lynch syndrome without germline mutation

M Rodríguez–Soler, L Pérez–Carbonell, C Guarinos… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Colorectal cancers (CRCs) with microsatellite instability (MSI) and
a mismatch repair (MMR) immunohistochemical deficit without hypermethylation of the …

The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status

R Jover, P Zapater, A Castells, X Llor, M Andreu… - European journal of …, 2009 - Elsevier
AIMS: The aim of this study is to evaluate if mismatch repair (MMR) defective colorectal
cancer has a different response to adjuvant 5-fluorouracil (5-FU) chemotherapy in a cohort …

5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer

R Jover, TP Nguyen, L Pérez–Carbonell, P Zapater… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: 5-Fluorouracil (5-FU)–based adjuvant chemotherapy does not
increase survival times of patients with colorectal tumors with microsatellite instability. We …

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with …

L Pérez-Carbonell, C Ruiz-Ponte, C Guarinos… - Gut, 2012 - gut.bmj.com
Background The selection of patients for genetic testing to rule out Lynch syndrome is
currently based on fulfilment of at least one of the revised Bethesda criteria followed by …

Performance of different microsatellite marker panels for detection of mismatch repair–deficient colorectal tumors

RM Xicola, X Llor, E Pons, A Castells… - Journal of the …, 2007 - academic.oup.com
Background Colorectal tumors caused by failure of the DNA mismatch repair system
commonly show microsatellite instability. Our goals were to compare the performance of two …

Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology

S Benlloch, A Payá, C Alenda, X Bessa… - The Journal of Molecular …, 2006 - Elsevier
Mutation V600E of BRAF, a kinase-encoding gene from the RAS/RAF/MAPK pathway, in
colorectal carcinoma (CRC) suggests a sporadic origin of the disease, providing an …

Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study

F Balaguer, S Castellví–Bel, A Castells… - Clinical …, 2007 - Elsevier
Background & Aims: Whereas it has conclusively been demonstrated that biallelic MutY
human homolog (MYH) mutations confer a significant risk for colorectal cancer (CRC), the …