Effect of colour of drugs: systematic review of perceived effect of drugs and of their effectiveness

AJM De Craen, PJ Roos, AL De Vries, J Kleijnen - Bmj, 1996 - bmj.com
Objectives: To assess the impact of the colour of a drug9s formulation on its perceived effect
and its effectiveness and to examine whether antidepressant drugs available in the …

Cerebral blood flow in small vessel disease: a systematic review and meta-analysis

Y Shi, MJ Thrippleton, SD Makin… - Journal of cerebral …, 2016 - journals.sagepub.com
White matter hyperintensities are frequent on neuroimaging of older people and are a key
feature of cerebral small vessel disease. They are commonly attributed to chronic …

Is the assumed natural history of vulvar intraepithelial neoplasia III based on enough evidence? A systematic review of 3322 published patients

M van Seters, M van Beurden, AJM de Craen - Gynecologic oncology, 2005 - Elsevier
OBJECTIVE: To establish the true natural history of VIN III from literature data. METHODS: In
a systematic review, data of women with VIN III indexed in several computer databases were …

Genetic studies of body mass index yield new insights for obesity biology

AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers… - Nature, 2015 - nature.com
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials

N Sattar, D Preiss, HM Murray, P Welsh, BM Buckley… - The Lancet, 2010 - thelancet.com
Background Trials of statin therapy have had conflicting findings on the risk of development
of diabetes mellitus in patients given statins. We aimed to establish by a meta-analysis of …

Thyroid status, disability and cognitive function, and survival in old age

J Gussekloo, E van Exel, AJM de Craen, AE Meinders… - Jama, 2004 - jamanetwork.com
ContextDespite the equivocal outcomes of randomized controlled trials, general clinical
opinion favors screening and treatment of elderly individuals with subclinical thyroid …

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze… - Nature, 2017 - nature.com
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at
risk of developing type 2 diabetes, cardiovascular disease and related metabolic and …

[HTML][HTML] Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

L Broer, V Codd, DR Nyholt, J Deelen… - European journal of …, 2013 - nature.com
Telomere length (TL) has been associated with aging and mortality, but individual
differences are also influenced by genetic factors, with previous studies reporting heritability …

Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old

DG Taekema, J Gussekloo, AB Maier… - Age and …, 2010 - academic.oup.com
Background: muscle wasting is associated with a detrimental outcome in older people.
Muscle strength measurements could be useful as part of a clinical evaluation of oldest old …

[HTML][HTML] Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult …

CHY Ling, AJM de Craen, PE Slagboom, DA Gunn… - Clinical nutrition, 2011 - Elsevier
BACKGROUND & AIMS: Body composition measurement is a valuable tool for assessing
nutritional status and physical fitness in a variety of clinical settings. Although bioimpedance …