[HTML][HTML] The PANcreatic Disease ReseArch (PANDoRA) consortium: Ten years' experience of association studies to understand the genetic architecture of pancreatic …

D Campa, M Gentiluomo, A Stein, MN Aoki… - Critical reviews in …, 2023 - Elsevier
Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of
risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of …

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

BM Wolpin, C Rizzato, P Kraft, C Kooperberg… - Nature …, 2014 - nature.com
We performed a multistage genome-wide association study including 7,683 individuals with
pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome …

Intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI) versus intravenous therapy (FOLFIRI) for hepatic metastases from colorectal cancer: final …

G Fiorentini, C Aliberti, M Tilli, L Mulazzani… - Anticancer …, 2012 - ar.iiarjournals.org
Background: Metastases to the liver receive most of their blood supply from the arterial route,
therefore for patients with hepatic metastases from large bowel cancer, hepatic arterial …

Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the …

C Cremolini, C Antoniotti, D Rossini, S Lonardi… - The Lancet …, 2020 - thelancet.com
Background The triplet FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus
bevacizumab showed improved outcomes for patients with metastatic colorectal cancer …

Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer

EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger… - Nature …, 2015 - nature.com
Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both
inherited high-penetrance mutations in BRCA2 (ref.), ATM, PALB2 (ref.), BRCA1 (ref.) …

[HTML][HTML] Multidisciplinary approach of colorectal cancer liver metastases

G Fiorentini, D Sarti, C Aliberti… - World journal of …, 2017 - ncbi.nlm.nih.gov
Large bowel cancer is a worldwide public health challenge. More than one third of patients
present an advanced stage of disease at diagnosis and the liver is the most common site of …

[HTML][HTML] Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

AP Klein, BM Wolpin, HA Risch… - Nature …, 2018 - nature.com
Abstract In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe
and the United States combined. To identify common susceptibility alleles, we performed the …

Pet therapy effects on oncological day hospital patients undergoing chemotherapy treatment

M Orlandi, K Trangeled, A Mambrini… - Anticancer …, 2007 - ar.iiarjournals.org
Background: Pet therapy is utilised to improve the quality of life of patients with chronic
diseases. The impact of AAA (animal-assisted activities), a kind of pet therapy, on …

[HTML][HTML] Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32. 1, 5p15. 33 and 8q24. 21

M Zhang, Z Wang, O Obazee, J Jia, EJ Childs… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Genome-wide association studies (GWAS) have identified common pancreatic cancer
susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify …

[HTML][HTML] Maintenance sunitinib or observation in metastatic pancreatic adenocarcinoma: a phase II randomised trial

M Reni, S Cereda, M Milella, A Novarino… - European Journal of …, 2013 - Elsevier
Background New strategies to prolong disease control warrant investigation in patients with
metastatic pancreatic adenocarcinoma. This open-label, randomised, multi-centre phase II …