Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1–positive acute lymphoblastic …
…, C Papayannidis, A Lonoce… - Blood, The Journal …, 2009 - ashpublications.org
The BCR-ABL1 fusion gene defines the subgroup of acute lymphoblastic leukemia (ALL)
with the worst clinical prognosis. To identify oncogenic lesions that combine with BCR-ABL1 …
with the worst clinical prognosis. To identify oncogenic lesions that combine with BCR-ABL1 …
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure
CT Storlazzi, A Lonoce, MC Guastadisegni… - Genome …, 2010 - genome.cshlp.org
Double minutes (dmin) and homogeneously staining regions (hsr) are the cytogenetic
hallmarks of genomic amplification in cancer. Different mechanisms have been proposed to …
hallmarks of genomic amplification in cancer. Different mechanisms have been proposed to …
MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene
…, T Fioretos, C Surace, A Lonoce… - Human molecular …, 2006 - academic.oup.com
Abstract Double minutes (dmin)—circular, extra-chromosomal amplifications of specific
acentric DNA fragments—are relatively frequent in malignant disorders, particularly in solid …
acentric DNA fragments—are relatively frequent in malignant disorders, particularly in solid …
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer
…, G Macchia, P D'Addabbo, A Lonoce… - Nucleic acids …, 2014 - academic.oup.com
The mechanism for generating double minutes chromosomes (dmin) and homogeneously
staining regions (hsr) in cancer is still poorly understood. Through an integrated approach …
staining regions (hsr) in cancer is still poorly understood. Through an integrated approach …
[HTML][HTML] MYC-containing amplicons in acute myeloid leukemia: genomic structures, evolution, and transcriptional consequences
…, PD′ Addabbo, D Traversa, G Daniele, A Lonoce… - Leukemia, 2018 - nature.com
Double minutes (dmin), homogeneously staining regions, and ring chromosomes are
vehicles of gene amplification in cancer. The underlying mechanism leading to their …
vehicles of gene amplification in cancer. The underlying mechanism leading to their …
Comparative mapping of human alphoid sequences in great apes using fluorescence in situ hybridization
…, R Antonacci, R Marzella, P Finelli, A Lonoce… - Genomics, 1995 - Elsevier
Twenty-seven human alphoid DNA probes have been hybridized in situ to metaphase
spreads of the common chimpanzee (PTR), the pigmy chimpanzee (PPA), and the gorilla …
spreads of the common chimpanzee (PTR), the pigmy chimpanzee (PPA), and the gorilla …
CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia
MC Guastadisegni, A Lonoce, L Impera, F Di Terlizzi… - Leukemia, 2010 - nature.com
AML1, maps at 21q22. 3 and encodes a transcription factor crucial for normal
hematopoiesis. It is frequently involved in gene fusions resulting from 35 different …
hematopoiesis. It is frequently involved in gene fusions resulting from 35 different …
Upregulation of the SOX5 by promoter swapping with the P2RY8 gene in primary splenic follicular lymphoma
…, C Doglioni, MC Guastadisegni, L Impera, A Lonoce… - Leukemia, 2007 - nature.com
30: 274–282. 4 Meyer-Monard S, Muhlematter D, Streit A, Chase AJ, Gratwohl A, Cross NCP
et al. Broad molecular screening of an unclassifiable myeloproliferative disorder reveals an …
et al. Broad molecular screening of an unclassifiable myeloproliferative disorder reveals an …
t (3; 12)(q26; q14) in polycythemia vera is associated with upregulation of the HMGA2 gene
CT Storlazzi, F Albano, C Locunsolo, A Lonoce… - Leukemia, 2006 - nature.com
Polycythemia vera (PV) is a chronic myeloproliferative disorder (MPD) characterized by an
excess production of apparently normal erythrocytes and a variable overproduction of …
excess production of apparently normal erythrocytes and a variable overproduction of …
Structural organization of multiple alphoid subsets coexisting on human chromosomes 1, 4, 5, 7, 9, 15, 18, and 19
P Finelli, R Antonacci, R Marzella, A Lonoce… - Genomics, 1996 - Elsevier
FISH experiments on metaphase chromosomes, interphase nuclei, and extended chromatin
were performed to investigate the structural organization of alphoid subsets coexisting on …
were performed to investigate the structural organization of alphoid subsets coexisting on …