Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
…, J Duce, PS Harper, A Lesley Jones - Human molecular …, 1999 - academic.oup.com
We detected an interaction of the N-terminus of huntingtin (htt171) with the C-terminal region
of the nuclear receptor co-repressor (N-CoR) using the yeast two-hybrid system. This …
of the nuclear receptor co-repressor (N-CoR) using the yeast two-hybrid system. This …
Age of onset in Huntington disease: sex specific influence of apolipoprotein E genotype and normal CAG repeat length
Age of onset (AO) of Huntington disease (HD) is known to be correlated with the length of an
expanded CAG repeat in the HD gene. Apolipoprotein E (APOE) genotype, in turn, is known …
expanded CAG repeat in the HD gene. Apolipoprotein E (APOE) genotype, in turn, is known …
Huntingtin interacts with cystathionine β-synthase
JM Boutell, JD Wood, PS Harper… - Human molecular …, 1998 - academic.oup.com
We have screened a rat brain library to identify proteins which interact with the 5′-end of
huntingtin (amino acids 1–171), including the polyglutamine tract, in the yeast two-hybrid …
huntingtin (amino acids 1–171), including the polyglutamine tract, in the yeast two-hybrid …
Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain
JD Wood, JC MacMillan, PS Harper… - Human molecular …, 1996 - academic.oup.com
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by the
expansion of a CAG repeat in a gene coding for a protein of unknown function. We have …
expansion of a CAG repeat in a gene coding for a protein of unknown function. We have …
Insoluble TATA-binding protein accumulation in Huntington's disease cortex
Huntington's disease is a dominantly inherited neurological disorder where specific
neurodegeneration is caused by an extended polyglutamine stretch in the huntingtin protein …
neurodegeneration is caused by an extended polyglutamine stretch in the huntingtin protein …
Lipid composition of the brown algae Fucus vesiculosus and Ascophyllum nodosum
AL Jones, JL Harwood - Phytochemistry, 1992 - Elsevier
The lipid composition of the two brown marine algae, Fucus vesiculosus and Ascophyllum
nodosum, was very similar. The major acyl lipids were monogalactosyldiacylglycerol …
nodosum, was very similar. The major acyl lipids were monogalactosyldiacylglycerol …
The localization and interactions of huntingtin
AL Jones - … Transactions of the Royal Society of London …, 1999 - royalsocietypublishing.org
Huntingtin was localized by using a series of antibodies that detected different areas of the
protein from the immediate N–terminus to the C–terminal region of the protein. The more C …
protein from the immediate N–terminus to the C–terminal region of the protein. The more C …
Lipid Metabolism in the Brown Marine Algae Fucus vesiculosus and Ascophyllum nodosum
AL JONES, JL HARWOOD - Journal of experimental Botany, 1993 - academic.oup.com
Lipid metabolism and environmental effects on this process have been studied in the marine
brown algae Fucus vesiculosus and Ascophyllum nodosum. These algae showed very …
brown algae Fucus vesiculosus and Ascophyllum nodosum. These algae showed very …
Novel inhibitors of the condensing enzymes of the type II fatty acid synthase of pea (Pisum sativum)
AL JONES, D HERBERT, AJ RUTTER… - Biochemical …, 2000 - portlandpress.com
The type II fatty acid synthases (FASs) of higher plants (and Escherichia coli) contain three
condensing enzymes called β-ketoacyl-ACP synthases (KAS), where ACP is acyl-carrier …
condensing enzymes called β-ketoacyl-ACP synthases (KAS), where ACP is acyl-carrier …
Molecular investigation of TBP allele length:: A SCA17 cellular model and population study
Recently, an inherited spinocerebellar ataxia (SCA17) has been attributed to polyglutamine
coding expansions within the gene coding for human TATA-box binding protein (TBP). The …
coding expansions within the gene coding for human TATA-box binding protein (TBP). The …