More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers
G Dolton, K Tungatt, A Lloyd, V Bianchi… - …, 2015 - Wiley Online Library
Analysis of antigen‐specific T‐cell populations by flow cytometry with peptide–MHC (pMHC)
multimers is now commonplace. These reagents allow the tracking and phenotyping of T …
multimers is now commonplace. These reagents allow the tracking and phenotyping of T …
Induction and exhaustion of lymphocytic choriomeningitis virus–specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex …
A Gallimore, A Glithero, A Godkin, AC Tissot… - The Journal of …, 1998 - rupress.org
This study describes the construction of soluble major histocompatibility complexes
consisting of the mouse class I molecule, H-2Db, chemically biotinylated β2 microglobulin …
consisting of the mouse class I molecule, H-2Db, chemically biotinylated β2 microglobulin …
[HTML][HTML] Home sweet home: the tumor microenvironment as a haven for regulatory T cells
B Ondondo, E Jones, A Godkin… - Frontiers in immunology, 2013 - frontiersin.org
CD4+ Foxp3+ regulatory T cells (Tregs) have a fundamental role in maintaining immune
balance by preventing autoreactivity and immune-mediated pathology. However this role of …
balance by preventing autoreactivity and immune-mediated pathology. However this role of …
Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2).
A Godkin, T Friede, M Davenport… - International …, 1997 - academic.oup.com
Abstract HLA-DQ8 (A1* 0301, B1* 0302) and-DQ2 (A1* 0501, B1* 0201) are both
associated with diseases such as insulin-dependent diabetes mellitus and coeliac disease …
associated with diseases such as insulin-dependent diabetes mellitus and coeliac disease …
Regulatory T cells and tumour immunity–observations in mice and men
A Gallimore, A Godkin - Immunology, 2008 - Wiley Online Library
An enormous body of work supports a role for CD4+ CD25+ regulatory cells (Tregs) in
shaping the immune response to tumours. Indeed, there is evidence that the cells impede …
shaping the immune response to tumours. Indeed, there is evidence that the cells impede …
In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope
RP Anderson, P Degano, AJ Godkin, DP Jewell… - Nature medicine, 2000 - nature.com
Celiac disease (CD) is an increasingly diagnosed enteropathy (prevalence, 1: 200–1: 300) 1
that is induced by dietary exposure to wheat gliadins 2 (as well as related proteins in rye and …
that is induced by dietary exposure to wheat gliadins 2 (as well as related proteins in rye and …
COVID‐19 vaccine response in people with multiple sclerosis
…, K George, G Giovannoni, A Godkin… - Annals of …, 2022 - Wiley Online Library
Objective The purpose of this study was to investigate the effect of disease modifying
therapies on immune response to severe acute respiratory syndrome‐coronavirus 2 (SARS …
therapies on immune response to severe acute respiratory syndrome‐coronavirus 2 (SARS …
VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium
Here, we report an update of the VDJdb database with a substantial increase in the number
of T-cell receptor (TCR) sequences and their cognate antigens. The update further provides …
of T-cell receptor (TCR) sequences and their cognate antigens. The update further provides …
Severe acute bovine viral diarrhea in Ontario, 1993–1995
…, R Tremblay, S Bolin, A Godkin… - Journal of …, 1998 - journals.sagepub.com
In 1993, noncytopathic bovine viral diarrhea virus (BVDV) strains with enhanced virulence
caused unprecedented outbreaks of severe acute bovine viral diarrhea (BVD) in dairy, beef …
caused unprecedented outbreaks of severe acute bovine viral diarrhea (BVD) in dairy, beef …
[HTML][HTML] CD4+CD25+FOXP3+ Regulatory T Cells Suppress Anti-Tumor Immune Responses in Patients with Colorectal Cancer
SL Clarke, GJ Betts, A Plant, KL Wright… - PloS one, 2006 - journals.plos.org
Background A wealth of evidence obtained using mouse models indicates that CD4+
CD25+ FOXP3+ regulatory T cells (Treg) maintain peripheral tolerance to self-antigens and …
CD25+ FOXP3+ regulatory T cells (Treg) maintain peripheral tolerance to self-antigens and …