Hamartomatous polyposis syndromes are a diverse group of inherited conditions grouped
together because they exhibit hamartomatous rather than epithelial polyp histology. Each …

BACKGROUND As panel testing becomes more common in clinical practice, it is important
to understand the prevalence and trends associated with the pathogenic variants (PVs) …

Cowden syndrome (CS) is an often difficult to recognize hereditary cancer predisposition
syndrome caused by mutations in phosphatase and tensin homolog deleted on …

One size does not fit all for breast cancer screening. Early detection and prevention are most
effective for those most at risk. Several United States organizations recommend offering …

Background The growing demand for cancer genetic services underscores the need to
consider approaches that enhance access and efficiency of genetic counseling. Telephone …

Purpose The ongoing integration of cancer genomic testing into routine clinical care has led
to increased demand for cancer genetic services. To meet this demand, there is an urgent …

Purpose To inform development of a culturally sensitive hereditary breast and ovarian
cancer communication initiative and related clinical genetic services. Methods Five focus …

Osteoarthritis (OA) is the fastest growing cause of disability worldwide. The aim of this study
was to understand the impact of OA on individuals and to explore current treatment …

Patients with germline mutations in one of the SDH genes are at substantially increased risk
of developing paragangliomas, pheochromocytomas (pheos), and other tumors (all …

In this paper, I (1) offer a general introduction of rewilding and (2) situate the concept in
environmental philosophy. In the first part of the paper, I work from definitions and typologies …