Double heterozygotes for the Ashkenazi founder mutations in BRCA1 and BRCA2 genes

Am J Hum Genet. 1998 Oct;63(4):1224-7. doi: 10.1086/302040.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • BRCA2 Protein
  • Breast Neoplasms / genetics
  • Europe / ethnology
  • Female
  • Founder Effect*
  • Genes, BRCA1*
  • Heterozygote
  • Humans
  • Israel
  • Jews / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Neoplasm Proteins / genetics*
  • Ovarian Neoplasms / genetics
  • Transcription Factors / genetics*

Substances

  • BRCA2 Protein
  • Neoplasm Proteins
  • Transcription Factors