Tetrasomy 21 as a sole abnormality in erythroleukemia

A M Udayakumar; T S Sundareshan

doi:10.1016/0165-4608(95)00114-x

Tetrasomy 21 as a sole abnormality in erythroleukemia

Cancer Genet Cytogenet. 1995 Nov;85(1):85-7. doi: 10.1016/0165-4608(95)00114-x.

Authors

A M Udayakumar¹, T S Sundareshan

Affiliation

¹ Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.

PMID: 8536246
DOI: 10.1016/0165-4608(95)00114-x

Abstract

A 13-year-old girl presented with swelling in the neck, fever, bleeding of the gums, and hepatosplenomegaly. Bone marrow morphology was suggestive of erythroleukemia (AML-M6). Chromosome analysis of the marrow revealed 48,XX, +21, +21 as the sole clonal abnormality.

Publication types

Case Reports

MeSH terms

Adolescent
Aneuploidy*
Bone Marrow / ultrastructure
Chromosomes, Human, Pair 21*
Female
Humans
Karyotyping
Leukemia, Erythroblastic, Acute / genetics*
Leukemia, Erythroblastic, Acute / pathology