Chromosomal translocation t(13;16) in a patient with idiopathic hypogonadotropic hypogonadism

Intern Med. 1993 Jun;32(6):465-7. doi: 10.2169/internalmedicine.32.465.

Abstract

A patient with idiopathic hypogonadotropic hypogonadism (IHH) had an apparently balanced reciprocal translocation involving chromosomes 13 and 16 [t(13;16)(q14.11;q24)]. The patient's father has the same chromosomal translocation with no apparent physical abnormalities. The role of the chromosomal translocation in this patient is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chromosome Aberrations / genetics*
  • Chromosome Disorders
  • Chromosomes, Human, Pair 13 / ultrastructure*
  • Chromosomes, Human, Pair 16 / ultrastructure*
  • Ejaculation
  • Erectile Dysfunction / genetics*
  • Follicle Stimulating Hormone / deficiency
  • Gonadotropin-Releasing Hormone / deficiency*
  • Humans
  • Hypogonadism / genetics*
  • Kallmann Syndrome / genetics
  • Luteinizing Hormone / deficiency
  • Male
  • Pedigree
  • Pituitary Hormone-Releasing Hormones
  • Testosterone / deficiency
  • Translocation, Genetic*

Substances

  • Pituitary Hormone-Releasing Hormones
  • Gonadotropin-Releasing Hormone
  • Testosterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone