Abstract
A highly polymorphic CA repeat was identified in a cosmid containing the 5' end of the NF2 tumour suppressor gene. This marker has proved useful in presymptomatic diagnosis in affected families.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alleles
-
Base Sequence
-
Genes, Neurofibromatosis 2 / genetics*
-
Genetic Markers
-
Humans
-
Membrane Proteins / genetics*
-
Molecular Sequence Data
-
Neoplasm Proteins / genetics*
-
Neurofibromatosis 2 / diagnosis
-
Neurofibromatosis 2 / genetics*
-
Neurofibromin 2
-
Polymorphism, Genetic
-
Repetitive Sequences, Nucleic Acid
Substances
-
Genetic Markers
-
Membrane Proteins
-
Neoplasm Proteins
-
Neurofibromin 2