Isochromosome for the long arm of the Y in an infertile male

Hum Genet. 1978 Jan 19;40(2):227-30. doi: 10.1007/BF00272306.

Abstract

A 37-year-old man investigated for infertility had bilateral atrophic testes. Cytogenetic investigations revealed a chromosome complement of 45,XO/46,Xi(Yq)/46,XY. Mechanisms for the origin of the i(Yq) are considered, and the relation of his chromosome constitution to his infertility and hypogonadism are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atrophy
  • Humans
  • Infertility, Male / genetics*
  • Male
  • Sex Chromosome Aberrations / complications*
  • Sex Chromosomes*
  • Testis / pathology
  • Y Chromosome*