Somatic mutation analysis in NF1 café au lait spots reveals two NF1 hits in the melanocytes

J Invest Dermatol. 2008 Apr;128(4):1050-3. doi: 10.1038/sj.jid.5701095. Epub 2007 Oct 4.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biopsy
  • Cafe-au-Lait Spots / genetics*
  • Cafe-au-Lait Spots / pathology
  • DNA Mutational Analysis
  • Female
  • Humans
  • Loss of Heterozygosity
  • Male
  • Melanocytes / metabolism*
  • Melanocytes / pathology
  • Microsatellite Repeats
  • Middle Aged
  • Mutation*
  • Neurofibromin 1 / genetics*

Substances

  • Neurofibromin 1