Abstract
Two new studies reveal a novel connection between transcription and pre-mRNA processing: the Paf1 elongation complex is involved in the 3' end formation of polyadenylated and nonpolyadenylated RNA polymerase II transcripts.
MeSH terms
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Gene Expression Regulation
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Humans
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Nuclear Proteins / genetics
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Nuclear Proteins / metabolism*
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RNA 3' End Processing / physiology*
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RNA Polymerase II / metabolism*
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RNA Processing, Post-Transcriptional / physiology*
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RNA, Messenger / genetics
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RNA, Messenger / metabolism*
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Saccharomyces cerevisiae / enzymology
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism
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Saccharomyces cerevisiae Proteins / genetics
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Saccharomyces cerevisiae Proteins / metabolism*
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Transcription Factors
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Transcription, Genetic
Substances
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Nuclear Proteins
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PAF1 protein, S cerevisiae
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PAF1 protein, human
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RNA, Messenger
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Saccharomyces cerevisiae Proteins
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Transcription Factors
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RNA Polymerase II