Effect of the antimalarial drug halofantrine in the long QT syndrome due to a mutation of the cardiac sodium channel gene SCN5A

Am J Cardiol. 2001 Apr 1;87(7):909-11. doi: 10.1016/s0002-9149(00)01538-1.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Amino Acid Sequence
  • Antimalarials / adverse effects*
  • Electrocardiography
  • Female
  • Humans
  • Long QT Syndrome / genetics*
  • Male
  • Molecular Sequence Data
  • Mutation
  • NAV1.5 Voltage-Gated Sodium Channel
  • Pedigree
  • Phenanthrenes / adverse effects*
  • Sodium Channels / genetics*
  • Tachycardia, Ventricular / chemically induced*

Substances

  • Antimalarials
  • NAV1.5 Voltage-Gated Sodium Channel
  • Phenanthrenes
  • SCN5A protein, human
  • Sodium Channels
  • halofantrine