Inflated false-positive rates in Hardy-Weinberg and linkage-equilibrium tests are due to sampling on the basis of rare familial phenotypes in finite populations

Am J Hum Genet. 2000 Jul;67(1):258-9. doi: 10.1086/302964.
No abstract available

Publication types

  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping / methods*
  • Chromosome Mapping / statistics & numerical data
  • Genetic Predisposition to Disease / genetics
  • Humans
  • Linkage Disequilibrium / genetics*
  • Patient Selection*
  • Quantitative Trait, Heritable*
  • Reproducibility of Results
  • Sample Size
  • Sampling Studies