Neuropediatrics 2000; 31(4): 214-217
DOI: 10.1055/s-2000-7462
Short Communication

Georg Thieme Verlag Stuttgart · New York

Complicated Hereditary Spastic Paraplegia with Peripheral Neuropathy, Optic Atrophy and Mental Retardation

Sahoko Miyama1 , Kiyoshi Arimoto1 , Satoshi Kimiya1 , Hideaki Tomi2
  • 1 Department of Pediatric Neurology, Shimada Center for Rehabilitation and Neurodevelopmental Intervention, Tokyo, Japan
  • 2 Tomi Clinic, Tokyo, Japan
Further Information

Publication History

Publication Date:
31 December 2000 (online)

An 8-year old girl with a not previously described type of complicated hereditary spastic paraplegia (HSP) is presented. Spasticity in her lower limbs had already been recognized during infancy and worsened progressively. Severe delay in mental development was observed. Peripheral neuropathy and optic atrophy developed at 5 years of age. On brain magnetic resonance imaging, an abnormally thin corpus callosum was observed. Involvement of the fasciculus gracilis was suggested by somatosensory evoked potentials. To our knowledge, there has been no reported case of complicated HSP with peripheral neuropathy, optic atrophy and mental retardation so far. We postulate that our patient is a sporadic case of not previously described complicated HSP.

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M. D. Sahoko Miyama

Department of Pediatric Neurology Shimada Center for Rehabilitation and Neurodevelopmental Intervention

1-31-1 Nakazawa

Tama-shi

Tokyo 206-0036

Japan

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