Abstract
The presence of distal atretic vagina causing accumulation of fluid and mucus secretions in the proximal vaginal cavity resulted in fetal hydrocolpos. Obstructive uropathy developed gradually because of direct compression of hydrocolpos on bilateral lower ureters, resulting in oligohydramnios from decreased urine formation. Oligohydramnios inhibited normal mandibular development with resulting cleft palate and glossoptosis (Pierre Robin Sequence). The development of sequence of events in this case indicates Pierre Robin Sequence as another effect of Oligohydramnios Sequence arising out of deformational forces acting on cranio-facial structures.
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References
Mahoney PJ, Chamberlain JW . Hydrometrocolpos in infancy: congenital atresia of the vagina with abnormally abundant cervical secretions. J Pediatr 1940; 17: 772
Mirk P, Pintus C, Speca S . Ultrasound diagnosis of hydrocolpos: prenatal findings and postnatal follow-up. J Clin Ultrasound 1994; 22: 55–8.
Taylor MR . The Pierre Robin Sequence: a concise review for the practicing pediatrician. Pediatr Rev 2001; 22(4): 125–30.
Godefrey M . Imperforation de la membrane hymens. Lancette Francaise. Gasette Das Hop Civ Mil 1856; 29: 567
Liu WF, Borrego O, Weiss M, Sweet CR . Lethal pulmonary hypoplasia and hydrocolpos with transverse vaginal septum in a newborn: a case report and review of the literature. J Perinatol 1999; 19(6): 454–9.
Reed MH, Griscom NT . Hydrometrocolpos in infancy. Am J Roentgenol 1973; 118: 1–13.
Ogunyemi D . Prenatal sonographic diagnosis of bladder outlet obstruction caused by a ureterocele associated with hydrocolpos and imperforate hymen. Am J Perinatol 2001; 18: 15–21.
Black ARN, Sanders RC, Gearhart JP . Obstructed uterovaginal anomalies: demonstration with sonography. Radiology 1991; 179: 79–83.
Cook GT, Marshall VF . Hydrocolpos causing urinary obstruction. J Urol 1964; 92: 127–32.
Rodriguez JI, Palacios J . Pathogenetic mechanisms of fetal akinesia deformation sequence and Oligohydramnios Sequence. Am J Med Genet 1991; 40: 284–9.
Thomas IT, Smith DW . Oligohydramnios, cause of the nonrenal features of Potter's syndrome, including pulmonary hypoplasia. J Pediatr 1974; 84(6): 811–4.
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Aggarwal, S., Kumar, A. Fetal Hydrocolpos Leading to Pierre Robin Sequence: An Unreported Effect of Oligohydramnios Sequence. J Perinatol 23, 76–78 (2003). https://doi.org/10.1038/sj.jp.7210846
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DOI: https://doi.org/10.1038/sj.jp.7210846
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