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ACE inhibitor bulks up muscle

A drug commonly used to treat high blood pressure shows promise as a treatment in mouse models of Marfan syndrome and muscular dystrophy (pages 204–210).

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Figure 1: Increased TGF-β activity can inhibit muscle regeneration by blocking activation of satellite cells, as shown by Cohn et al1;.

Katie Ris

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Chamberlain, J. ACE inhibitor bulks up muscle. Nat Med 13, 125–126 (2007). https://doi.org/10.1038/nm0207-125

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