Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Mediating mismatch repair

Abstract

The DNA repair picture in humans becomes more complete with the identification of MLH3, a homologue of MutL and a heterodimeric partner of MLH1.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Dao, V. & Modrich, P. J. Biol. Chem. 273, 9202–9207 (1998).

    Article  CAS  Google Scholar 

  2. Lipkin, S.M. et al. Nature Genet. 24, 27– 35 (2000).

    Article  CAS  Google Scholar 

  3. Jiricny, J. EMBO J. 17, 6427–6436 ( 1998).

    Article  CAS  Google Scholar 

  4. Kunkel, T.A. Nature 365, 207–208 ( 1993).

    Article  CAS  Google Scholar 

  5. Kolodner, R.D. et al. Cancer Res. 59, 5068– 5074 (1999).

    CAS  PubMed  Google Scholar 

  6. de Wind, N. et al. Nature Genet. 23, 359– 362 (1999).

    Article  CAS  Google Scholar 

  7. Edelmann, W. et al. Cell 91, 467–477 (1997).

    Article  CAS  Google Scholar 

  8. Räschle, M. et al. J. Biol. Chem. 274, 32368– 32375 (1999).

    Article  Google Scholar 

  9. Li, G.M. & Modrich, P. Proc. Natl Acad. Sci. USA 92, 1950–1954 (1995).

    Article  CAS  Google Scholar 

  10. Flores-Rozas, H. & Kolodner, R.D. Proc. Natl Acad. Sci. USA 95, 12404–12409 (1998).

    Article  CAS  Google Scholar 

  11. Yao, X. et al. Proc. Natl Acad. Sci. USA 96, 6850– 6855 (1999).

    Article  CAS  Google Scholar 

  12. Prolla, T.A. et al. Nature Genet. 18, 276– 279 (1998).

    Article  CAS  Google Scholar 

  13. D'Atri, S. et al. Mol. Pharmacol. 54, 334– 341 (1998).

    Article  CAS  Google Scholar 

  14. Duckett, D.R. et al. Proc. Natl Acad. Sci. USA 96, 12384 –12388 (1999).

    Article  CAS  Google Scholar 

  15. Hickman, M.J. & Samson, L.D. Proc. Natl Acad. Sci. USA 96, 10764–10769 (1999).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jiricny, J. Mediating mismatch repair. Nat Genet 24, 6–8 (2000). https://doi.org/10.1038/71698

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/71698

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing