Molecular Cell
Volume 75, Issue 2, 25 July 2019, Pages 252-266.e8
ArticleTopoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
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Graphical Abstract
Keywords
topoisomerase
topoisomerase 2 cleavage complex
DNA double-strand breaks
cohesin
3D chromatin organization
transcription
chromosomal translocations
proteasome
TDP2
quantitative modeling
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