Original articleClinical endoscopyLymph node metastasis in multiple synchronous early gastric cancer
Section snippets
Patients and treatment
From August 2005 to December 2009, cases of patients with EGC who were enrolled at Seoul National University Hospital were reviewed. From the electronic medical records, a total of 2240 patients with pathologically confirmed EGC were eligible for the study. All patients underwent curative treatment by surgery or endoscopic resection, depending on the conventional indications for endoscopic resection,3 the results of pretreatment staging (abdominal multiple-detector row CT, and/or EUS),
Clinicopathologic characteristics
A total of 1717 patients (156 in the multiple EGC group and 1561 in the solitary EGC group) were included in the study. Among the patients with multiple EGCs, partial gastrectomy was performed in 115 (73.7%), and total gastrectomy was performed in 41 (26.3%). A total of 343 lesions in 156 patients with multiple EGCs were detected: 2 lesions (n = 135), 3 (n = 16), 4 (n = 3), and >5 lesions (n = 2). Compared with solitary EGCs, multiple EGCs occurred in older patients and were more common in men.
Discussion
Although the indications for endoscopic resection in EGC have progressively expanded, the specific indication criteria for multiple EGCs have not been determined. The results of the present study suggest that the clinicopathologic features of multiple EGCs were not significantly different from those of solitary EGCs, with the same risk of LN metastasis between groups.
The incidence of multiple synchronous EGC was 7.7% (173/2240 patients) in our study, which was in agreement with a previous
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DISCLOSURE: All authors disclosed no financial relationships relevant to this publication.