Elsevier

Fertility and Sterility

Volume 84, Issue 3, September 2005, Pages 758-760
Fertility and Sterility

Correspondence
Screening the SPO11 and EIF5A2 genes in a population of infertile men

Presented at the 59th Annual Meeting of the American Society for Reproductive Medicine, San Antonio, Texas, October 11–15, 2003.
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Populations of infertile and fertile men were screened for mutations in SPO11 and EIF5A2, two infertility candidate genes. Three heterozygous amino acid changes that might contribute to infertility were identified in the infertile group.

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Supported by National Institutes of Health grant GM48152 and Science Foundation Ireland. Control samples obtained from the Utah Genetic Reference Project (UGRP) were collected with support from a Public Health Services research grant to the Huntsman General Clinical Research Center, number M01-RR00064, from the National Center for Research Resources. The UGRP was also supported by generous gifts from the W.M. Keck and Delores Dore Eccles Foundations.