Mini reviewFunctions of Fibroblast Growth Factor Receptors in cancer defined by novel translocations and mutations
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Leandro H. Gallo is a graduate student researcher in the Donoghue group in the Department of Chemistry & Biochemistry at the University of California, San Diego. He obtained his B.S. degree in Biological Sciences from Hunter College, City University of New York. He is currently in his fourth year of doctoral thesis studying the activation of IKKbeta, the regulatory kinase of the NFkappaB inflammatory signaling pathway, via a novel Lys63-linked ubiquitin modification.
Katelyn N. Nelson is a graduate student in the Donoghue group in the Department of Chemistry & Biochemistry at the University of California, San Diego. She earned her B.S. in Biochemistry at California State University, Long Beach. Her research focuses on identifying and characterizing novel oncogenic signaling mechanisms and interactions, specifically in the FGFR pathway.
April N. Meyer is a Staff Research Associate in Dr. Daniel J. Donoghue's laboratory at the University of California, San Diego. She earned her B.S. degree from the University of California, San Diego in the Department of Chemistry & Biochemistry. Her areas of expertise include cell biology and FGFR signaling.
Daniel J. Donoghue received his Ph.D. from MIT in 1979, after which he conducted postdoctoral research at the Salk Institute for Biological Studies. He has been on the faculty of UC San Diego since 1982. He has had a long-standing interest in Receptor Tyrosine Kinases (RTKs) and their roles in development and oncogenesis, especially the Fibroblast Growth Factor Receptors (FGFR). Currently, his lab exploits proteomic and genomic approaches to identify novel sites of posttranslational modifications, protein–protein interactions, and gene interaction networks.