Elsevier

The Breast

Volume 13, Issue 1, February 2004, Pages 77-79
The Breast

CASE REPORT
Gynaecomastia, neurofibromatosis and breast cancer

https://doi.org/10.1016/j.breast.2003.08.002Get rights and content

Abstract

Gynaecomastia commonly affects pubertal boys. We report a rare case of bilateral ductal carcinoma in situ found incidentally after breast reduction surgery in a young man with neurofibromatosis.

Section snippets

Case report

An 18-year-old male with Neurofibromatosis Type 1 was referred for surgical treatment of bilateral ductal carcinoma in situ (DCIS) discovered unexpectedly through cosmetic breast reduction surgery.

MH had presented to his general practitioner at the age of 10 complaining of “lumps under his skin”. On examination the general practitioner had found cutaneous stigmata of neurofibromatosis including café-au-lait spots, axillary freckling and neurofibromata. Review by a paediatrician confirmed the

Acknowledgements

The authors would like to thank Miss C.A. Reid, Miss P. Bond and the late Professor Sloan of the Royal Liverpool University Hospital, for their help in the management of this case.

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There are more references available in the full text version of this article.

Cited by (23)

  • Gynaecomastia revealing neurofibromatosis type 1 in a young child

    2009, European Journal of Radiology Extra
    Citation Excerpt :

    A case of von Recklinghausen disease presented as a neurofibrosarcoma of the breast has been reported, as well as that of a primary malignant schwannoma of the breast [10,13]; the etiology of malignant transformation may be post traumatic or associated with incomplete surgical excision. Wilson et al. has reported a case of bilateral ductal carcinoma in situ (DCIS), in an 18-year-old male with neurofibromatosis type 1, and he concluded that there is a synergy between the NF1 gene and a breast cancer predisposition gene [14]. Treatment of breast neurofibromas is carried out through surgical excision [5].

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