Elsevier

The Journal of Pediatrics

Volume 80, Issue 2, February 1972, Pages 292-297
The Journal of Pediatrics

Brief clinical and laboratory observation
Infancy-onset diabetes mellitus and multiple epiphyseal dysplasia*

https://doi.org/10.1016/S0022-3476(72)80596-1Get rights and content

Summary

Three siblings with onset of diabetes mellitus infancy are reported. Two (and possibly all three) of the children also had multiple epiphyseal dysplasia. Demineralization of the bone with multiple fractures, tooth discoloration, and skin abnormalities were also observed. A unifying biochemical or physiologic mechanism for the simultaneous appearance of diabetes, epiphyseal dysplasia, and possible ectodermal dysplasia has not suggested itself, but this may represent a new syndrome.

References (4)

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    Acta Paediatr.

    (1949)
  • ImerslundO.

    The prognosis in diabetical with onset before age two

    Acta paediatr.

    (1960)
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*

Supported in part by a grant from The Kroc Foundation.

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