Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain

doi:10.1016/0896-6273(92)90210-5

Neuron

Volume 8, Issue 5, May 1992, Pages 957-966

https://doi.org/10.1016/0896-6273(92)90210-5 Get rights and content

Abstract

We have previously characterized a novel transcription factor family in mammals, the HNF-3 family, by the members' homology to one another and to the Drosophila homeotic gene fork head. The expression of fork head is restricted to the anterior and posterior termini of the early fly embryo. Brain factor 1 (BF-1) is a new member of this family isolated from rat brain with an expression pattern and DNA binding specificity distinct from the HNF-3 genes. Expression is highly restricted in the developing neural tube to its rostral end, which gives rise to the telencephalon. These results suggest that BF-1 plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.

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Neuron

ArticleTelencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain

Abstract

Anal. Biochem.

Cell

Cell

Neuron

Cell

Cell

Cell

Neuron

Gene

Gene

J. Mol. Biol.

Cell

Cell

Cell

Transcriptional control of the mouse prealbumin (transthyretin) gene: both promoter sequences and a distinct enhancer are cell specific

Mol. Cell Biol.

Multiple hepatocyte-specfic nuclear factors function in the regulation of the transthyretin and a1-antitrypsin genes

Mol. Cell Biol.

Expression patterns of the homeo box-containing genes En-1 and En-2 and the protooncogene int-1 diverge during mouse development

Genes Dev.

Expression of the homeo-box containing gene En-2 delineates a specific region of the developing mouse brain

Genes Dev.

The murine Hox gene network: its structural and functional organization resembles that of the Drosophila homeotic genes

EMBO J.

Rat DARPP-32: cloning, sequencing and characterization of cDNA

J. Mol. Neurosci.

Article
Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain