PUBLIC HEALTHPrenatal screening for cystic fibrosis
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Cited by (133)
Expanded Carrier Screening
2019, Fetal Medicine: Basic Science and Clinical PracticeCost-effectiveness of carrier screening for cystic fibrosis in Australia
2012, Journal of Cystic FibrosisCitation Excerpt :Despite this technological advance, there have been few population-based carrier screening programs introduced. An early pilot program in Edinburgh used a couple screening model and halved the live birth incidence of CF [3]. Fee for service pre-conception and prenatal screening are widely practiced in the United States, but do not receive government subsidy.
Benchmarks for Cystic Fibrosis carrier screening: A European consensus document
2010, Journal of Cystic FibrosisCitation Excerpt :These are: The identification of an individual as a carrier raises anxiety, although this is often dispelled if the partner tests negative, and does not seem to be long lasting [42–46] Discrimination as a result of identification as a carrier: by creating a difficulty for finding a partner if tested before partnering; by limiting health and life insurance options; or by limiting reproductive options [47,48]
Time Trends in Birth Incidence of Cystic Fibrosis in Two European Areas: Data from Newborn Screening Programs
2008, Journal of PediatricsCitation Excerpt :In the Veneto region, the first terminations after prenatal carrier testing were performed in 2000, and since that year half of the terminations have been in couples whose 1-in-4 risk was identified by such testing. Some pilot experiences of prenatal screening have been set up in different areas, with the first established in the Edinburgh area (Scotland) in 1990.20 After implementation of that program, the number of CF children diagnosed per year decreased by 65% (from 4.6 in 1984 to 1990 to 1.6 in 1991 to 1995).21
Factors affecting decisions to accept or decline cystic fibrosis carrier testing/screening: A theory-guided systematic review
2007, Genetics in MedicineCitation Excerpt :Weak perceived susceptibility of being a CF carrier (HBM factor; 10%): Cuckle et al.48 found that pregnant women refused to be tested because they did not feel that CF was a common disease. Attitudes against abortion (non-HBM factor; 10%): women who were against termination of an affected pregnancy had a negative attitude toward CF carrier testing in three studies.4,48,49 Ethnicity (HBM modifying factor; 10%): nonwhites were more likely to decline testing.34,37,38
Screening for Cystic Fibrosis Carrier Status
2006, When to Screen in Obstetrics and Gynecology