Skip to main content
Log in

Vesico-ureteral reflux: a genetic condition?

  • REVIEW
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Vesico-ureteral reflux (VUR) is a frequent condition, but in most instances, the precise cause is unknown. We here review the evidence of a genetic aetiology of VUR, inherited as an autosomal dominant trait, with variable expression. We discuss the possible pathogenetic relationship between VUR and other types of uropathies and possible strategies towards the identification of genes underlying VUR are presented. The isolation of the gene(s) responsible for uropathies will not only lead to a better insight into the embryology of the urological system, the pathogenesis of uropathies, but also to a renewed interest from clinicians in congenital uropathies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

Authors

Additional information

Received: 5 September 1997 / Accepted in revised form: 29 September 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Devriendt, K., Groenen, P., Van Esch, H. et al. Vesico-ureteral reflux: a genetic condition?. Eur J Pediatr 157, 265–271 (1998). https://doi.org/10.1007/s004310050808

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004310050808

Navigation