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Linear growth in patients with Turner syndrome: Influence of spontaneous puberty and parental height

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Abstract

Growth data on 100 patients with Turner syndrome are reported. Seventeen had spontaneous puberty. Between the ages 11 and 13 years, height and height velocity were higher in these girls than in those with induced puberty. Final adult height, however, was not different. Patients disomic for Xp chromosome were taller than the monosomic ones, and the majority of them had spontaneous puberty. Significant positive correlations were found between height of Turner syndrome patients and corrected mid parental height, mother's height and father's height from the age of 6 years. It is concluded that in patients with Turner syndrome spontaneous puberty and parental height should be accounted for in the evaluation of linear growth.

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Abbreviations

CMPH:

corrected mid parental height

FH:

father's height

MH:

mother's height

SDS:

standard deviation score

References

  1. Baudier MM, Chihal J, Dickey RP (1985) Pregnancy and reproductive function in a patient with nonmosaic Turner syndrome. Obstet Gynecol 65:60S-64S

    PubMed  Google Scholar 

  2. Brook CGD, Mürset G, Zachmann M, Prader A (1974) Growth in children with 45,X0 Turner's syndrome. Arch Dis Child 49: 789–795

    PubMed  Google Scholar 

  3. Brook CGD, Gasser T, Werder EA, Prader A, Vanderschueren-Lodeweyckx MA (1977) Height correlations between parents and mature offspring in normal subjects and in subjects with Turner's and Klinefelter's and other syndromes. Ann Hum Biol 4:17–22

    PubMed  Google Scholar 

  4. Demetriou E, Emans SJ, Crigler JF (1984) Final height in estrogen-treated patients with Turner syndrome. Obstet Gynecol 64:459–464

    PubMed  Google Scholar 

  5. Ferguson-Smith MA (1969) Phenotypic aspects of sex chromosome aberrations. Birth Defects V, 5:3–9

    Google Scholar 

  6. Lemli L, Smith DW (1963) The X0 syndrome: a study of the differentiated phenotype in 25 patients. J Pediatr 63:577–588

    PubMed  Google Scholar 

  7. Lenko HL, Söderholm A, Perheentupa J (1988) Turner syndrome: effect of hormone therapies on height velocity and adult height. Acta Paediatr Scand 77:699–704

    PubMed  Google Scholar 

  8. Lyon AJ, Preece MA, Grant DB (1985) Growth curve for girls with Turner syndrome. Arch Dis Child 60:932–935

    PubMed  Google Scholar 

  9. Massa G, Dooms L, Vanderschueren-Lodeweyckx M (1988) Puberty and growth in girls with Turner syndrome (in Dutch). Tijdschr Geneesk 44:669–676

    Google Scholar 

  10. Nielsen J, Sillesen I, Hansen KB (1979) Fertility in women with Turner's syndrome: case report and review of literature. Br J Obstet Gynaecol 86:833–835

    PubMed  Google Scholar 

  11. Park E, Bailey JD, Cowell CA (1983) Growth and maturation of patients with Turner's syndrome. Pediatr Res 17:1–7

    PubMed  Google Scholar 

  12. Pelz L, Timm D, Eyermann E, Hinkel GK, Kirchner M, Verron G (1982) Body height in Turner's syndrome. Clin Genet 22:62–66

    PubMed  Google Scholar 

  13. Ranke MB, Pflüger H, Rosendahl W, Stubbe P, Enders H, Bierich LR, Majewski F (1983) Turner syndrome: spontaneous growth in 150 cases and review of the literature. Eur J Pediatr 141:81–88

    Article  PubMed  Google Scholar 

  14. Salerno MC, Job JC (1987) La taille dans le syndrome de Turner: corrélations avec la taille des parents. Arch Fr Pediatr 44:863–866

    PubMed  Google Scholar 

  15. Snider ME, Solomon IL (1974) Ultimate height in chromosomal gonadal dysgenesis without androgen therapy. Am J Dis Child 127:673–674

    PubMed  Google Scholar 

  16. Tanner JM (1962) Growth at adolescence. Blackwell, Oxford

    Google Scholar 

  17. Tanner JM, Whitehouse RH, Takaishi M (1966) Standards from birth to maturity for height, weight, height velocity and weight velocity: British children 1965. Arch Dis Child 41:454–471

    PubMed  Google Scholar 

  18. Tanner JM, Goldstein H, Whitehouse RH (1970) Standards for children's height at ages 2–9 years allowing for height of parents. Arch Dis Child 45:755–762

    PubMed  Google Scholar 

  19. Toublanc JE, Doyard PA, Canlorbe P, Job JC (1984) Fréquence et degré du développement pubertaire au cours du syndrome de Turner. Ann Pediatr 31:237–242

    Google Scholar 

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Massa, G., Vanderschueren-Lodeweyckx, M. & Malvaux, P. Linear growth in patients with Turner syndrome: Influence of spontaneous puberty and parental height. Eur J Pediatr 149, 246–250 (1990). https://doi.org/10.1007/BF02106283

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  • DOI: https://doi.org/10.1007/BF02106283

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