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Assignment of human β-galactosidase-A gene to 3p21.33 by fluorescence in situ hybridization

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Abstract

GM1 gangliosidosis and Morquio syndrome type B (MPS IVB) are inherited lyosomal storage disorders associated with deficiency of β-galactosidase-A (βGALA) activity. A recombinant plasmid containing a biotinylated cDNA (2.4-kb insert) encoding human β GALA was used to localize the enzyme locus by fluorescence in situ hybridization (FISH). The human β GALA gene was assigned to 3p21.33 by FISH.

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  1. Department of Hygiene, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, 173, Tokyo, Japan

    Takako Takano & Yasuko Yamanouchi

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  1. Takako Takano
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  2. Yasuko Yamanouchi
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Takano, T., Yamanouchi, Y. Assignment of human β-galactosidase-A gene to 3p21.33 by fluorescence in situ hybridization. Hum Genet 92, 403–404 (1993). https://doi.org/10.1007/BF01247344

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  • DOI: https://doi.org/10.1007/BF01247344

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