Summary
An Indiana family segregating a syndrome of X-linked mental retardation and skeletal anomalies was tested for linkage of the mutant gene to X-chromosome molecular markers. Lod scores of 3.27 and 3.06 (Θ-0) for the molecular probes St14-1 (DXS52) and Dx13 (DXS15), respectively, indicate that the disease gene is located in the terminal portion of Xq.
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Dlouhy, S.R., Christian, J.C., Haines, J.L. et al. Localization of the gene for a syndrome of X-linked skeletal dysplasia and mental retardation to Xq27-qter. Hum Genet 75, 136–139 (1987). https://doi.org/10.1007/BF00591074
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DOI: https://doi.org/10.1007/BF00591074