Elsevier

Genomics

Volume 47, Issue 2, 15 January 1998, Pages 314-318
Genomics

SHORT COMMUNICATION
An Expression Map from Human Chromosome 14q24.3

https://doi.org/10.1006/geno.1997.5106Get rights and content
Under a Creative Commons license
open archive

Abstract

We have constructed an expression map of chromosome 14q24.3 between markers D14S42 and D14S63. cDNA selection with YACs from 14q24.3 was used to generate expressed sequence tags (ESTs). The localization of ESTs was confirmed on a YAC contig. PCR products of ESTs were used as probes to screen cDNA libraries leading to the isolation of transcripts for known and unknown genes. In total, the expression map contains 7 known genes previously mapped to 14q24.3, 6 cDNA transcripts, and 15 anonymous ESTs. The addition of 21 unique transcribed loci from an ≈5- to 7-Mb region of chromosome 14q24.3 will facilitate future efforts to identify human disease genes from this region.

Cited by (0)

Sequence data from this article have been deposited with the EMBL/GenBank Data Libraries under Accession Nos. G20215–G20218, N64901–N64914, N65920–N65937, N81199–N81206, U25972, and W33209.

1

To whom correspondence should be addressed at present address: PPD Discovery Inc., 1505 O'Brien Drive, Suite B, Menlo Park, CA 94025. Telephone: (415) 617-9570. Fax: (415) 617-9574.

2

Present address: Institute of Molecular Biology and Biochemistry, Department of Chemistry, Simon Fraser University, Burnaby BC, Canada V5A156.