Brief CommunicationAstrocytes and Microglia Respond to Estrogen with Increased apoE mRNAin Vivoandin Vitro☆
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2023, International Journal of Biological MacromoleculesSporadic Alzheimer’s triad: Age, sex, and ApoE
2021, Assessments, Treatments and Modeling in Aging and Neurological Disease: The Neuroscience of AgingTibolone attenuates inflammatory response by palmitic acid and preserves mitochondrial membrane potential in astrocytic cells through estrogen receptor beta
2019, Molecular and Cellular EndocrinologyA Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward
2019, NeuronCitation Excerpt :Investigators have only begun to scratch the surface of why this might be the case. Some evidence suggests that APOE expression is impacted by estradiol (Lambert et al., 2004; Levin-Allerhand et al., 2001; Srivastava et al., 2008; Stone et al., 1997; Struble et al., 2003). In this age of enormous AD GWAS meta-analyses, the role of the X chromosome variants remains essentially unexplored (note that the Manhattan plots in all the large AD GWAS papers only show chromosomes 1–22) (Lambert et al., 2013; Marioni et al., 2018).
Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors
2016, Frontiers in Neuroendocrinology
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E. Knobil, Eds.J. D. Neill, Eds.
- 1
Both authors contributed equally and share first authorship.
- 2
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