low penetrance alleles

Specific polymorphisms in the RETproto-oncogene are over-represented in patients with Hirschsprung disease and may represent loci modifying phenotypic expression
Salud Borrego, María Eugenia Sáez, Agustín Ruiz, Oliver Gimm, Manuel López-Alonso, Guillermo Antiñolo, Charis Eng

Journal of Medical Genetics Oct 1999, 36 (10) 771-774; DOI: 10.1136/jmg.36.10.771

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low penetrance alleles