Clinical and molecular features of five patients harbouring TP53 p.Arg337His
| Sample ID | Age at diagnosis, sex | Sarcoma histology | Other tumours | Family history of cancer (relative, age) | XAF1:p.Glu134Ter | Clinical criteria |
| GRY_7 | 26–30, M | LMS | No | Gastric cancer (grandfather, 91–95) | Present | None |
| GRY_22 | 26–30, F | LMS | No | Breast cancer (paternal aunt, 26–30); CNS tumour (paternal aunt, 31–35); gastric cancer (maternal grandfather, NA) | Present | Chompret (2015) |
| GRY_23 | 31–35, M | LMS | No | Prostate cancer and sarcoma (father, 56–60, 61–65); laryngeal neoplasia (maternal grandmother, 71–75 smoker); glioblastoma (paternal cousin, 31–35); Hodgkin lymphoma (paternal cousin, 21–25); colorectal cancer (paternal uncle, 46–50 years); leukaemia (paternal uncle, 0–5); colorectal cancer (paternal grandfather, 55–60). | Absent | Chompret (2015) |
| GRY_327 | 31–35, F | LPS | No | Breast cancer and thyroid carcinoma (mother, 40s); lung cancer (maternal grandmother, 66–70); breast cancer (maternal great-aunt, 61–65); colorectal cancer (maternal great-aunt, 56–50); uterine cancer (maternal great-aunt, 46–50 years); CNS tumour (maternal cousin, 0–5). | Present | Chompret (2015) |
| GRY_369 | 21–25, M | OS | No | Lung cancer (maternal aunt, NA). | Present | None |
CNS, central nervous system; F, female; LMS, leiomyosarcoma; LPS, liposarcoma; M, male; NA, not available; OS, osteosarcoma.