Table 2

Clinical features of 177 young patients with sarcomas with and without GPV

FeaturesTotal patients
N (%)
With GPV
N (%)
Without GPV
N (%)
P value
Total individuals177 (100%)38 (21.5%)139 (78.5%)
Sex0.32
 F97 (54.8%)24 (63.2%)73 (52.5%)
 M80 (45.2%)14 (36.8%)66 (47.5%)
Mean age (range)26 (0–54*)27 (6–54*)26 (0–41)0.94
Age group0.58
 C (0–14 years)36 (20.3%)6 (15.8%)30 (21.6%)
 AYA (15–40* years)141 (79.7%)32 (84.2%)109 (78.4%)
Other primary tumours0.012
 Positive17 (9.6%)8 (21.1%)9 (6.5%)
 Negative160 (90.3%)30 (78.9%)130 (93.5%)
Family history of cancer0.64
 Positive72 (40.7%)15 (39.5%)57 (41.0%)
 Negative28 (15.8%)4 (10.5%)24 (17.3%)
 No information77 (43.5%)19 (50.0%)58 (41.7%)
  • *A female patient with a chondrosarcoma diagnosed at her early 50s was included. This case was prospectively included considering her family history of cancer, in which her father had a chondrosarcoma at his early 20s and was not available for germline material collection (deceased).

  • AYA, adolescents and young adults; C, children.