Clinical features of 177 young patients with sarcomas with and without GPV
Features | Total patients N (%) | With GPV N (%) | Without GPV N (%) | P value |
Total individuals | 177 (100%) | 38 (21.5%) | 139 (78.5%) | |
Sex | 0.32 | |||
F | 97 (54.8%) | 24 (63.2%) | 73 (52.5%) | |
M | 80 (45.2%) | 14 (36.8%) | 66 (47.5%) | |
Mean age (range) | 26 (0–54*) | 27 (6–54*) | 26 (0–41) | 0.94 |
Age group | 0.58 | |||
C (0–14 years) | 36 (20.3%) | 6 (15.8%) | 30 (21.6%) | |
AYA (15–40* years) | 141 (79.7%) | 32 (84.2%) | 109 (78.4%) | |
Other primary tumours | 0.012 | |||
Positive | 17 (9.6%) | 8 (21.1%) | 9 (6.5%) | |
Negative | 160 (90.3%) | 30 (78.9%) | 130 (93.5%) | |
Family history of cancer | 0.64 | |||
Positive | 72 (40.7%) | 15 (39.5%) | 57 (41.0%) | |
Negative | 28 (15.8%) | 4 (10.5%) | 24 (17.3%) | |
No information | 77 (43.5%) | 19 (50.0%) | 58 (41.7%) |
*A female patient with a chondrosarcoma diagnosed at her early 50s was included. This case was prospectively included considering her family history of cancer, in which her father had a chondrosarcoma at his early 20s and was not available for germline material collection (deceased).
AYA, adolescents and young adults; C, children.