Performance of EUR PRS when excluding the Polish and Israeli cohorts from the discovery set and using these respective populations as the target cohorts
| Method | Target set cohort | OR per 1 SD | Top 10% OR |
| P+T (EUR) | BCAC-IL | 1.37±0.06 | 2.41±0.76 |
| BCAC-PL | 1.46±0.06 | 2.2±0.15 | |
| P+T target LD | BCAC-IL | 1.36±0.03 | 1.64±0.17 |
| BCAC-PL | 1.5±0.07 | 1.85±0.16 | |
| LDPred | BCAC-IL | 1.31±0.1 | 1.56±0.17 |
| BCAC-PL | 1.17±0.06 | 1.82±0.33 | |
| Lassosum | BCAC-IL | 1.50±0.06 | 1.82±0.3 |
| BCAC-PL | 1.53±0.05 | 3.11±0.45 |
Shown are average ORs per 1 SD and top 10% ORs. Errors were measured using SEM for the six holdout sets.
BCAC-IL, BCAC cohort from Israel; BCAC-PL, BCAC cohort from Poland; P+T, pruning and thresholding; P+T target LD, pruning and thresholding using linkage disequilibrium of the target population.