Published studies on APC I1307K in AJ or Israeli (ethnicity not reported) extracolonic cancer patients and cancer-free controls
| Study | Ashkenazi Jewish individuals or Israelis (ethnicity not determined) | ||
| Extracolonic ca. I1307K/total (%) | Controls I1307K/total (%) | OR (95% CI), p value* | |
| Stern et al (2001)(AJ)28 | 2/11 (18.2) | 17/209 (8.1) | 2.49 (0.24 to 13.54), p=0.2433 |
| Forkosh et al (2022) (AJ)10 | 441/6318 (7.0) | 342/4918 (7.0) | 1.00 (0.87 to 1.17), p=0.9702 |
| Liberman et al (2007) (Israeli)49 | 32/404 (7.9) | 266/3283 (8.1) | 0.98 (0.64 to 1.44), p=1.00 |
| Leshno et al (2016) (Israeli)45 | 113/976 (11.6) | 614/13 013 (4.7) | 2.64 (2.12 to 3.28), p<2.2e-16 |
| Total | 588/7709 (7.6) | 1239/21 423 (5.8) | 1.35 (1.21 to 1.49), p=1.883e-08 |
| Total (only AJs) | 443/6329 (7.0) | 359/5127 (7.0) | 1.00 (0.86 to 1.16), p=1 |
*Fisher’s exact test. Calculations made for this publication. Results may not coincide with the original publications due to the application of different adjustments to the tests in their analyses.
AJ, Ashkenazi Jewish.